February 24, 2024
musagenomics

Spectrum of PAH gene mutations and genotype-phenotype

Spectrum of PAH gene mutations and genotype-phenotype correlation in patients with phenylalanine hydroxylase deficiency from Shanxi province

Background: Phenylalanine hydroxylase deficiency (PAHD) is an autosomal recessive inborn error that affects phenylalanine (Phe) metabolism. It has a complex phenotype with many variants and genotypes among different populations. Shanxi province is a high-prevalence area of PAHD in China.
Methods: In this study, eighty-nine PAHD patients were subjected to genetic testing using Sanger sequencing, followed by multiplex ligation-dependent probe amplification analysis (MLPA). Allelic and genotypic phenotype values (APV and GPV, respectively) were used for genotype-based phenotypic prediction.
Results: Fifty-one types of variants, including three novel forms, were identified. The predominant variant was p.R243Q (22.09%), followed by p.R53H (10.47%), p.EX6-96A > G (9.30%), p.V399V (5.23%) and p.R413P (3.49%). Notably, mild hyperphenylalaninemia (MHP) has a high prevalence in this region (up to 45.76%), and the variant p.R53H was solely observed in patients of MHP. According to the genotype-phenotype prediction, the APV/GPV system was well correlated with the metabolic phenotype of most PAHD patients.
Conclusion: We have systematically constructed the mutational and phenotypic spectrum of PAH in Shanxi province. Hence, this study will help to further understand the genotype-phenotype associations in PAHD patients, and it may offer more reliable genetic counseling and management.
musagenomics
musagenomics

Genome polyprotein Antibody

1-CSB-PA333180LA01HFD
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Unconjugated. Tested in the following application: ELISA

Genome polyprotein Antibody

1-CSB-PA362073LA01HQD
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Unconjugated. Tested in the following application: ELISA

Genome polyprotein Antibody

20-abx300967
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome polyprotein Antibody

CSB-PA4643XA11GSV 100ul / 50ul
EUR 299
  • 2-3 business days
Description: Genome polyprotein

Genome polyprotein Antibody

CSB-PA4644XA11GSW 100ul / 50ul
EUR 299
  • 2-3 business days
Description: Genome polyprotein

Genome polyprotein Antibody (HRP)

20-abx109095
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome polyprotein Antibody (HRP)

20-abx300968
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome polyprotein Antibody (FITC)

20-abx107678
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome polyprotein Antibody (FITC)

20-abx300969
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome polyprotein Antibody (Biotin)

20-abx106264
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome Polyprotein Antibody (Biotin)

20-abx105887
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome polyprotein Antibody (Biotin)

20-abx300970
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome Polyprotein Polyclonal Antibody

A68253
  • EUR 684.66
  • EUR 117.7
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody

A68254
  • EUR 684.66
  • EUR 117.7
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody

A56743
  • EUR 684.66
  • EUR 117.7
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody

A56130
  • EUR 684.66
  • EUR 117.7
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

Enterovirus 71 Genome polyprotein Antibody

20-abx109758
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome polyprotein Antibody, HRP conjugated

1-CSB-PA18549B0Rb
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is HRP conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, HRP conjugated

1-CSB-PA714772LB01HYH
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is HRP conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, HRP conjugated

1-CSB-PA333180LB01HFD
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is HRP conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, HRP conjugated

1-CSB-PA362073LB01HQD
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is HRP conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, FITC conjugated

1-CSB-PA18549C0Rb
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is FITC conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, FITC conjugated

1-CSB-PA714772LC01HYH
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is FITC conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, FITC conjugated

1-CSB-PA333180LC01HFD
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is FITC conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, FITC conjugated

1-CSB-PA362073LC01HQD
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is FITC conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, Biotin conjugated

1-CSB-PA18549D0Rb
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Biotin conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, Biotin conjugated

1-CSB-PA714772LD01HYH
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Biotin conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, Biotin conjugated

1-CSB-PA333180LD01HFD
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Biotin conjugated. Tested in the following application: ELISA

Genome polyprotein Antibody, Biotin conjugated

1-CSB-PA362073LD01HQD
  • EUR 380.4
  • EUR 402
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Biotin conjugated. Tested in the following application: ELISA

Genome Polyprotein (HCV-Core) Antibody

33487-05111 150 ug
EUR 313.2

Enterovirus 71 Genome polyprotein Antibody (HRP)

20-abx108220
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Enterovirus 71 Genome polyprotein Antibody (FITC)

20-abx106801
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Enterovirus 71 Genome polyprotein Antibody (Biotin)

20-abx105382
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Rhinovirus A serotype 89 Genome polyprotein Antibody

20-abx109372
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Hepatitis C Genome polyprotein

1-CSB-RP184674Ba
  • EUR 733.2
  • EUR 370.8
  • EUR 2192.4
  • EUR 1126.8
  • EUR 1461.6
  • EUR 476.4
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 71.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Hepatitis C Genome polyprotein expressed in E.coli

Genome Polyprotein Polyclonal Antibody, HRP Conjugated

A68252
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, HRP Conjugated

A68255
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, HRP Conjugated

A56744
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, HRP Conjugated

A56131
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP)

20-abx108723
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome Polyprotein Polyclonal Antibody, FITC Conjugated

A68251
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, FITC Conjugated

A68256
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, FITC Conjugated

A56745
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, FITC Conjugated

A56132
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC)

20-abx107303
  • EUR 493.2
  • EUR 2214
  • EUR 718.8
  • EUR 218.4
  • EUR 360
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Genome Polyprotein Polyclonal Antibody, Biotin Conjugated

A68250
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, Biotin Conjugated

A68257
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, Biotin Conjugated

A56746
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein Polyclonal Antibody, Biotin Conjugated

A56133
  • EUR 684.66
  • EUR 302.5
  • EUR 423.5
  • 100 µg
  • 50 ul
  • 100 ul

Genome Polyprotein (HCV-Core) Antibody (Biotin Conjugate)

33487-05121 150 ug
EUR 442.8

Yellow fever virus Genome polyprotein

1-CSB-EP365905YAC1
  • EUR 733.2
  • EUR 370.8
  • EUR 2192.4
  • EUR 1126.8
  • EUR 1461.6
  • EUR 476.4
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 78.4 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Yellow fever virus Genome polyprotein,partial expressed in E.coli

Human rhinovirus 1A Genome polyprotein

1-CSB-YP326367HQA
  • EUR 516
  • EUR 280.8
  • EUR 1809.6
  • EUR 770.4
  • EUR 1210.8
  • EUR 349.2
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 34.6 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human rhinovirus 1A Genome polyprotein,partial expressed in Yeast

Adaptation and validation of the Genetic Counseling Outcome Scale for autism spectrum disorders and related conditions

The genetics care pathway experienced by families affected by autism spectrum disorder (ASD) around the time of diagnosis is currently uncharacterized and potentially variable across contexts. The lack of consensus on outcome measures to capture the impact of genetic services for these families shows a gap in understanding and optimizing this genetics care pathway.
The Genetic Counseling Outcome Scale (GCOS-24) is a validated outcome measure of clinical genetics services. The current study aims to adapt and validate the GCOS-24 as an outcome measure in the context routine genetic testing in ASD and related conditions. Families seen for their child’s developmental evaluation for ASD and related conditions were invited to participate in a genomics cohort between 2016 and 2018. Families (n = 111) completed the mGCOS-24 (modified GCOS-24), adapted from the original GCOS-24 by clinicians working in the target population’s routine care pathway.
The mGCOS-24 has acceptable internal consistency (Cronbach’s α = 0.84) and high test-retest reliability (ICC = 0.88). It also inversely correlates with stress as measured by Perceived Stress Scale (PSS-10) and distress, as measured by the Distress Thermometer, rs ≥ 0.39, ps < 0.001. The mGCOS-24 had adequate readability, as supported by cognitive interviews completed by a sub-sample of five mothers of a child with ASD.
Together, our findings show that the mGCOS-24 has good validity for the target population. Preliminary characterization of the genetics care pathway in this population revealed remarkable variability in pre-test counseling and limited post-test counseling. The use of the mGCOS-24 as an outcome measure is useful in filling some of these gaps by offering a way to assess, and in the future, optimize the genetics care pathway for families affected by autism and related neurodevelopmental conditions.

Potential causes and consequences of rapid mitochondrial genome evolution in thermoacidophilic Galdieria (Rhodophyta)

  • Background: The Cyanidiophyceae is an early-diverged red algal class that thrives in extreme conditions around acidic hot springs. Although this lineage has been highlighted as a model for understanding the biology of extremophilic eukaryotes, little is known about the molecular evolution of their mitochondrial genomes (mitogenomes).
  • Results: To fill this knowledge gap, we sequenced five mitogenomes from representative clades of Cyanidiophyceae and identified two major groups, here referred to as Galdieria-type (G-type) and Cyanidium-type (C-type). G-type mitogenomes exhibit the following three features: (i) reduction in genome size and gene inventory, (ii) evolution of unique protein properties including charge, hydropathy, stability, amino acid composition, and protein size, and (iii) distinctive GC-content and skewness of nucleotides. Based on GC-skew-associated characteristics, we postulate that unidirectional DNA replication may have resulted in the rapid evolution of G-type mitogenomes.
  • Conclusions: The high divergence of G-type mitogenomes was likely driven by natural selection in the multiple extreme environments that Galdieria species inhabit combined with their highly flexible heterotrophic metabolism. We speculate that the interplay between mitogenome divergence and adaptation may help explain the dominance of Galdieria species in diverse extreme habitats.

PSMB8 antibody

70R-13550 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal PSMB8 antibody

PSMB8 antibody

70R-19589 50 ul
EUR 522
Description: Rabbit polyclonal PSMB8 antibody

PSMB8 Antibody

1-CSB-PA116429
  • EUR 380.4
  • EUR 292.8
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Antigen affinity purification
Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

PSMB8 Antibody

1-CSB-PA018886GA01HU
  • EUR 716.4
  • EUR 399.6
  • 150ul
  • 50ul
  • Form: Liquid
  • Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles. Antigen Affinity purified
Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF

PSMB8 Antibody

1-CSB-PA018886LA01HU
  • EUR 380.4
  • EUR 402
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

PSMB8 Antibody

1-CSB-PA775839
  • EUR 380.4
  • EUR 292.8
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Antigen affinity purification
Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

PSMB8 Antibody

E94054 100μg
EUR 255
Description: Available in various conjugation types.

PSMB8 Antibody

E97340 100ul
EUR 255
Description: Available in various conjugation types.

PSMB8 Antibody

E043134 100μg/100μl
EUR 255
Description: Available in various conjugation types.

PSMB8 Antibody

E314816 100ug/200ul
EUR 295
Description: Available in various conjugation types.

PSMB8 Conjugated Antibody

C43134 100ul
EUR 476.4

PSMB8 Polyclonal Antibody

A73468
  • EUR 377.3
  • EUR 577.5
  • 50 ul
  • 100 ul

PSMB8 Antibody, HRP conjugated

1-CSB-PA018886LB01HU
  • EUR 380.4
  • EUR 402
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

PSMB8 Antibody, FITC conjugated

1-CSB-PA018886LC01HU
  • EUR 380.4
  • EUR 402
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

PSMB8 Antibody, Biotin conjugated

1-CSB-PA018886LD01HU
  • EUR 380.4
  • EUR 402
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against PSMB8. Recognizes PSMB8 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Monoclonal PSMB8 Antibody, Clone: 1A5

AMM02864G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human PSMB8. The antibodies are raised in Mouse and are from clone 1A5. This antibody is applicable in WB and IHC, ICC, E

Mouse Monoclonal Antibody to PSMB8

E10-30255 100ul
EUR 225
Description: Available in various conjugation types.

Psmb8/ Rat Psmb8 ELISA Kit

ELI-15652r 96 Tests
EUR 1063.2

PSMB8

E8EM1709-54 100ul
EUR 275
Description: Available in various conjugation types.

PSMB8

enz-670 5µg
EUR 60
Description: Recombinant Human Proteasome Subunit Beta Type 8

Proteasome subunit beta type-8 (PSMB8) Antibody

20-abx211178
  • EUR 493.2
  • EUR 360
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Proteasome subunit beta type-8 (PSMB8) Antibody

20-abx211851
  • EUR 493.2
  • EUR 360
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Proteasome Subunit Beta Type-8 (PSMB8) Antibody

20-abx141396
  • EUR 444
  • EUR 727.2
  • EUR 360
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Proteasome Subunit Beta Type-8 (PSMB8) Antibody

20-abx114776
  • EUR 878.4
  • EUR 477.6
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Proteasome Subunit Beta Type-8 (PSMB8) Antibody

abx028154-400ul 400 ul
EUR 627.6
  • Shipped within 5-10 working days.

Proteasome Subunit Beta Type-8 (PSMB8) Antibody

abx028154-80l 80 µl
EUR 343.2
  • Shipped within 5-10 working days.

Proteasome Subunit Beta Type-8 (PSMB8) Antibody

20-abx006453
  • EUR 493.2
  • EUR 710.4
  • EUR 218.4
  • EUR 376.8
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Proteasome Subunit Beta Type-8 (PSMB8) Antibody

abx011689-100ul 100 ul
EUR 493.2
  • Shipped within 5-10 working days.

Monoclonal PSMB8 Antibody (monoclonal) (M01), Clone: 1B3

AMM03954G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PSMB8 (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 1B3. This antibody is applicable in WB, IHC and IF, IP, E

PSMB8 siRNA

20-abx930156
  • EUR 661.2
  • EUR 878.4
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

PSMB8 siRNA

20-abx930157
  • EUR 661.2
  • EUR 878.4
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

PSMB8 siRNA

20-abx904317
  • EUR 661.2
  • EUR 878.4
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

PSMB8 Rabbit pAb

A7340-100ul 100 ul
EUR 369.6

PSMB8 Rabbit pAb

A7340-200ul 200 ul
EUR 550.8

PSMB8 Rabbit pAb

A7340-20ul 20 ul
EUR 219.6

PSMB8 Rabbit pAb

A7340-50ul 50 ul
EUR 267.6

PSMB8 Rabbit pAb

E2507340 100ul
EUR 225
Description: Available in various conjugation types.

PSMB8 Blocking Peptide

BF0434-BP 1mg
EUR 234

PSMB8/LMP7 Mouse mAb

E2220606 100ul
EUR 225
Description: Available in various conjugation types.

PSMB8 protein (His tag)

80R-2608 100 ug
EUR 386.4
Description: Purified recombinant PSMB8 protein

PSMB8 / LMP7 Rabbit pAb

E2382339 100ul
EUR 225
Description: Available in various conjugation types.

Canine PSMB8 ELISA KIT

ELI-15651d 96 Tests
EUR 1113.6

Rat PSMB8 shRNA Plasmid

20-abx984734
  • EUR 961.2
  • EUR 1345.2
  • 150 µg
  • 300 µg
  • Shipped within 15-20 working days.

Human PSMB8 shRNA Plasmid

20-abx953843
  • EUR 961.2
  • EUR 1345.2
  • 150 µg
  • 300 µg
  • Shipped within 15-20 working days.

Mouse PSMB8 shRNA Plasmid

20-abx971337
  • EUR 961.2
  • EUR 1345.2
  • 150 µg
  • 300 µg
  • Shipped within 15-20 working days.

PSMB8 Recombinant Protein (Rat)

RP222629 100 ug Ask for price

PSMB8 Recombinant Protein (Mouse)

RP165287 100 ug Ask for price

PSMB8 Recombinant Protein (Human)

RP085356 100 ug Ask for price

Psmb8 ORF Vector (Rat) (pORF)

ORF074211 1.0 ug DNA
EUR 607.2

PSMB8 ORF Vector (Human) (pORF)

ORF028453 1.0 ug DNA
EUR 486

Psmb8 ORF Vector (Mouse) (pORF)

ORF055097 1.0 ug DNA
EUR 607.2

[KO Validated] PSMB8 Rabbit pAb

A19933-100ul 100 ul
EUR 492

[KO Validated] PSMB8 Rabbit pAb

A19933-200ul 200 ul
EUR 685.2

[KO Validated] PSMB8 Rabbit pAb

A19933-20ul 20 ul
EUR 265.2

[KO Validated] PSMB8 Rabbit pAb

A19933-50ul 50 ul
EUR 344.4

PSMB8 ELISA Kit (Dog) (OKEH03975)

OKEH03975 96 Wells
EUR 1012.8
Description: Description of target: ;Species reactivity: Dog;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.064 ng/mL

PSMB8 ELISA Kit (Human) (OKEH07770)

OKEH07770 96 Wells
EUR 1310.4
Description: Description of target: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.06ng/mL

PSMB8 ELISA Kit (Human) (OKCD02695)

OKCD02695 96 Wells
EUR 950.4
Description: Description of target: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells, substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency. Required for the differentiation of preadipocytes into adipocytes.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.117 ng/mL

Human PSMB8 Protein Lysate 20ug

IHUPSMB8PLLY20UG each
EUR 213
  • Wet Ice
Description: Human PSMB8 Protein Lysate 20ug

Proteasome 20S LMP7/PSMB8 Rabbit mAb

A23378 200μL
EUR 323.7
  • This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysoso
  • Show more
Description: A synthetic peptide corresponding to a sequence within amino acids 864-963 of human ApoER2/LRP8 (Q14114).

Psmb8 sgRNA CRISPR Lentivector set (Rat)

K6921501 3 x 1.0 ug
EUR 406.8

PSMB8 sgRNA CRISPR Lentivector set (Human)

K1740301 3 x 1.0 ug
EUR 406.8

Psmb8 sgRNA CRISPR Lentivector set (Mouse)

K4425601 3 x 1.0 ug
EUR 406.8

Psmb8 3'UTR GFP Stable Cell Line

TU266964 1.0 ml Ask for price

Psmb8 3'UTR GFP Stable Cell Line

TU167173 1.0 ml Ask for price

PSMB8 3'UTR GFP Stable Cell Line

TU069046 1.0 ml
EUR 1672.8

Rabbit Anti Human PSMB8 Monoclonal Clone AEFI-16

IRBAHUPSMB8AEFI16C100UL each
EUR 496
  • Dry Ice
Description: Rabbit Anti Human PSMB8 Monoclonal Clone AEFI-16

PSMB8 Protein Vector (Rat) (pPM-C-HA)

PV296844 500 ng
EUR 723.6

PSMB8 Protein Vector (Rat) (pPB-C-His)

PV296842 500 ng
EUR 723.6

PSMB8 Protein Vector (Rat) (pPB-N-His)

PV296843 500 ng
EUR 723.6

PSMB8 Protein Vector (Rat) (pPM-C-His)

PV296845 500 ng
EUR 723.6

PSMB8 Protein Vector (Human) (pPM-C-HA)

PV113812 500 ng
EUR 662.4

PSMB8 Protein Vector (Mouse) (pPM-C-HA)

PV220388 500 ng
EUR 723.6

PSMB8 Protein Vector (Human) (pPB-C-His)

PV113810 500 ng
EUR 662.4

PSMB8 Protein Vector (Human) (pPB-N-His)

PV113811 500 ng
EUR 662.4

PSMB8 Protein Vector (Human) (pPM-C-His)

PV113813 500 ng
EUR 662.4

PSMB8 Protein Vector (Mouse) (pPB-C-His)

PV220386 500 ng
EUR 723.6

PSMB8 Protein Vector (Mouse) (pPB-N-His)

PV220387 500 ng
EUR 723.6

PSMB8 Protein Vector (Mouse) (pPM-C-His)

PV220389 500 ng
EUR 723.6

Psmb8 3'UTR Luciferase Stable Cell Line

TU216964 1.0 ml Ask for price

Psmb8 3'UTR Luciferase Stable Cell Line

TU117173 1.0 ml Ask for price

PSMB8 3'UTR Luciferase Stable Cell Line

TU019046 1.0 ml
EUR 1672.8

Human Proteasome subunit beta type-8 (PSMB8)

1-CSB-EP018886HU
  • EUR 456
  • EUR 256.8
  • EUR 1570.8
  • EUR 672
  • EUR 1047.6
  • EUR 314.4
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 42.7 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Proteasome subunit beta type-8(PSMB8) expressed in E.coli

Psmb8 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6921502 1.0 ug DNA
EUR 184.8

Psmb8 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6921503 1.0 ug DNA
EUR 184.8

Psmb8 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6921504 1.0 ug DNA
EUR 184.8

PSMB8 sgRNA CRISPR Lentivector (Human) (Target 1)

K1740302 1.0 ug DNA
EUR 184.8

PSMB8 sgRNA CRISPR Lentivector (Human) (Target 2)

K1740303 1.0 ug DNA
EUR 184.8

PSMB8 sgRNA CRISPR Lentivector (Human) (Target 3)

K1740304 1.0 ug DNA
EUR 184.8

Psmb8 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4425602 1.0 ug DNA
EUR 184.8

Psmb8 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4425603 1.0 ug DNA
EUR 184.8

Psmb8 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4425604 1.0 ug DNA
EUR 184.8

Recombinant Human PSMB8 Protein, His, E.coli-1mg

QP13190-1mg 1mg
EUR 3308.4

Recombinant Human PSMB8 Protein, His, E.coli-5ug

QP13190-5ug 5ug
EUR 186

Recombinant Human PSMB8 Protein, His, E.coli-20ug

QP13190-20ug 20ug
EUR 241.2

PSMB8 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV700471 1.0 ug DNA
EUR 616.8

PSMB8 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV700475 1.0 ug DNA
EUR 616.8

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